Journal of Psychopharmacology Lifetime Classic Psychedelic Use and Headaches: A Cross-Sectional Study A cross-sectional study finds that lifetime psychedelic use is linked to a lower prevalence of frequent severe headaches, suggesting therapeutic potential.
Journal of Mental Health and Substance Research Psychedelic Pharmacology in Psychiatry: The Mechanisms and Therapeutic Potential of Psilocybin, MDMA, and LSD in Mental Health Disorders This review examines the mechanisms and therapeutic potential of psilocybin, MDMA, and LSD for depression, PTSD, and anxiety disorders.
BMC Medical Education Further Education in Psychedelic-Assisted Therapy – Experiences from Switzerland Examining Switzerland’s training framework for psychedelic-assisted therapy and its role in ensuring safe and effective clinical implementation.
The Arts in Psychotherapy ‘Go with the "wave of music" to dive deep’: Exploring perceptions of psychedelic-assisted therapy and the role of music within this practice This study explores how music shapes psychedelic-assisted therapy, serving as both a guide and container for emotional experiences.
Neuropharmacology Side Effects of Microdosing Lysergic Acid Diethylamide and Psilocybin: A Systematic Review of Potential Physiological and Psychiatric Outcomes A systematic review on the physiological and psychiatric side effects of microdosing LSD and psilocybin, including anxiety, BP increase, and cognitive impairment.
Neuroscience Applied A Review of Psychedelics Trials Completed in Depression, Informed by European Regulatory Perspectives A systematic review of completed psychedelics trials for depression, highlighting key findings and regulatory challenges.
Journal of Clinical Medicine Psychedelics and Suicide-Related Outcomes: A Systematic Review A systematic review evaluating the effects of psychedelics on suicide-related outcomes, highlighting potential benefits and risks of psilocybin, MDMA, and LSD.
Journal of Substance Abuse Treatment Preparations for Rave Music Parties and Consequences for Attendees Who Consume Psychedelic Drugs A study on psychedelic use at rave parties, examining pre-party preparations, post-party effects, and policy implications for harm reduction.
Clinical Pharmacology & Therapeutics Acute Effects and Pharmacokinetics of LSD after Paroxetine or Placebo Pre-Administration in a Randomized, Double-Blind, Cross-Over Phase I Trial A study examining the interaction of LSD and paroxetine finds reduced anxiety and nausea but unchanged pleasant effects. Paroxetine increases LSD levels via CYP2D6 inhibition.
bioRxiv Dissociable Effects of LSD and MDMA on Striato-Cortical Connectivity in Healthy Subjects A study finds LSD enhances sensory-cognitive connectivity, while MDMA reduces amygdala-limbic connectivity, with implications for therapy.
Journal of Neurochemistry Serotonergic Psychedelics Rapidly Modulate Evoked Glutamate Release in Cultured Cortical Neurons A study on how psychedelics modulate glutamate release in cortical neurons, highlighting their potential for treating depression and enhancing neuroplasticity.
Cancer Medicine Psychedelics for Cancer Pain and Associated Psychological Distress: A Narrative Review of a Potential Strategy A review of psychedelics for cancer pain and distress, highlighting their potential role in reducing pain perception and improving mood.
Psilocybin Into the Wild Frontier: Mapping the Terrain of Adverse Events in Psychedelic-Assisted Therapies This study aims to explore the risks associated with psychedelic-assisted therapies (PATs) by evaluating potential adverse events (AEs) to develop a comprehensive and standardized assessment framework.
Journal of Psychedelic Studies Experiences of Psychedelic Drug Use Among People with Psychotic Symptoms and Disorders: Personal Growth and Mystical Experiences A study reveals potential benefits and risks of psychedelics for individuals with psychotic disorders, emphasizing personal growth and mystical experiences.
Journal of Psychedelic Studies Psychedelic Intimacy: Altered States of Consciousness in Romantic Relationships This study explores how shared psychedelic experiences enhance emotional connection and communication in romantic relationships.
Journal of Psychedelic Studies LSD use in the United States: Examining user demographics and their evolution from 2015–2019 This study examines the demographic evolution of LSD users in the U.S. from 2015–2019, revealing a 47% increase in past-year use.
Psilocybin A Brief Review on the Potential of Psychedelics for Treating Alzheimer’s Disease and Related Depression This review investigates the potential role of psychedelics in addressing Alzheimer’s disease and associated depression, focusing on their neurochemical effects and therapeutic mechanisms.
Alzheimer’s Disease Psychedelics as a Treatment for Alzheimer’s Disease Dementia This study examines the potential of classical psychedelics, such as psilocybin and LSD, to treat Alzheimer’s disease, focusing on mechanisms like neurogenesis, neuroplasticity, and anti-inflammatory effects.